Organocatalytic Lewis base functionalisation of carboxylic acids, esters and anhydrides via C1-ammonium or azolium enolates.

نویسندگان

  • Louis C Morrill
  • Andrew D Smith
چکیده

This tutorial review highlights the organocatalytic Lewis base functionalisation of carboxylic acids, esters and anhydrides via C1-ammonium/azolium enolates. The generation and synthetic utility of these powerful intermediates is highlighted through their application in various methodologies including aldol-lactonisations, Michael-lactonisations/lactamisations and [2,3]-rearrangements.

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عنوان ژورنال:
  • Chemical Society reviews

دوره 43 17  شماره 

صفحات  -

تاریخ انتشار 2014